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Large parts of condensed matter theoretical physics and quantum chemistry have as a central goal discretizing and solving the continuum many-electron Schrodinger Equation. What do we want to get from these calculations? What are key problems of interest? What sort of approaches are used? I'll start with a broad overview of these questions using the renormalization group as a conceptual framework. I'll then progress towards our recent tensor network approaches for the many electron problem, discussing along the way issues of the area law, wavelet techniques and Wilson's related work, wavelets and MERA, and discretizations that combine grids and basis sets.